Compendium
Healing & Recovery

Larazotide (AT-1001)

Larazotide acetate is an 8-amino-acid peptide that acts as a tight junction regulator in the gut epithelium, showing promise for treating leaky gut syndrome and celiac disease.

Protocol

0.5–2 mg oral, 3x daily

Half-Life

2–4 hours

Molecular Structure & Chemistry

20 residues • 328 atoms • Skeletal Formula

Formula

C106H162N30O28S2

Molar Mass

2,008.45 g/mol

Exact Mass

2367.162 Da

Isoelectric Pt

9.77

Charge pH 7

+1.93

GRAVY

-0.33

Hover Cα carbons for residue info

Amino Acid Sequence

NKNGFNVYMTVCQQRIIPWG

Biological Mechanisms

Reduces intestinal permeability

Observed in clinical research as a primary mechanism of action for Larazotide (AT-1001).

Celiac disease management

Observed in clinical research as a primary mechanism of action for Larazotide (AT-1001).

Tight junction stabilization

Observed in clinical research as a primary mechanism of action for Larazotide (AT-1001).

Reduces GI inflammation

Observed in clinical research as a primary mechanism of action for Larazotide (AT-1001).

Safety & Risk Analysis

HeadacheDiarrheaNausea

Critical Safety Warning

Black market peptides can be contaminated, mislabeled, or dangerous. Only obtain peptides via a registered doctor and legitimate pharmacy. Never attempt self-administration without professional medical supervision.

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Quick Reference

CategoryHealing & Recovery
Half-Life2–4 hours
AdminSubcutaneous
Download Research PDF
Medical Note

This compound is for research purposes only. Clinical applications must be directed by a licensed physician.

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