Compendium
Cosmetic

Leuphasyl

Leuphasyl is a pentapeptide that modulates enkephalin receptors in muscle cells, reducing acetylcholine release and decreasing muscle contraction. Often combined with Argireline for synergistic wrinkle reduction.

Protocol

3–5% in topical formulations

Half-Life

N/A (topical)

Molecular Structure & Chemistry

12 residues • 188 atoms • Skeletal Formula

Formula

C55H95N17O17S4

Molar Mass

1,178.54 g/mol

Exact Mass

1393.598 Da

Isoelectric Pt

6.21

Charge pH 7

-0.06

GRAVY

+0.15

Hover Cα carbons for residue info

Amino Acid Sequence

NVREMVAMNPCM

Biological Mechanisms

Expression wrinkle reduction

Observed in clinical research as a primary mechanism of action for Leuphasyl.

Enkephalin receptor modulation

Observed in clinical research as a primary mechanism of action for Leuphasyl.

Synergistic with Argireline

Observed in clinical research as a primary mechanism of action for Leuphasyl.

Non-injectable

Observed in clinical research as a primary mechanism of action for Leuphasyl.

Skin smoothing

Observed in clinical research as a primary mechanism of action for Leuphasyl.

Safety & Risk Analysis

Well-tolerated topicallyRare mild irritation

Critical Safety Warning

Black market peptides can be contaminated, mislabeled, or dangerous. Only obtain peptides via a registered doctor and legitimate pharmacy. Never attempt self-administration without professional medical supervision.

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Quick Reference

CategoryCosmetic
Half-LifeN/A (topical)
AdminSubcutaneous
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Medical Note

This compound is for research purposes only. Clinical applications must be directed by a licensed physician.

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