Compendium
Cosmetic

Palmitoyl Tetrapeptide-7

Palmitoyl Tetrapeptide-7 (Rigin) is a lipopeptide fragment of IgG that suppresses excess IL-6, a key driver of skin inflammation and aging. Used with Matrixyl as Matrixyl 3000 to reduce puffiness.

Protocol

3–8% in topical formulations

Half-Life

N/A (topical)

Molecular Structure & Chemistry

20 residues • 315 atoms • Skeletal Formula

Formula

C105H148N26O33S3

Molar Mass

2,038.38 g/mol

Exact Mass

2396.988 Da

Isoelectric Pt

3.69

Charge pH 7

-1.07

GRAVY

-0.7

Hover Cα carbons for residue info

Amino Acid Sequence

GKTYSAQMNADYMWCWQSDI

Biological Mechanisms

Reduces skin inflammation

Observed in clinical research as a primary mechanism of action for Palmitoyl Tetrapeptide-7.

IL-6 suppression

Observed in clinical research as a primary mechanism of action for Palmitoyl Tetrapeptide-7.

Puffiness reduction

Observed in clinical research as a primary mechanism of action for Palmitoyl Tetrapeptide-7.

Synergistic anti-aging

Observed in clinical research as a primary mechanism of action for Palmitoyl Tetrapeptide-7.

Improved skin texture

Observed in clinical research as a primary mechanism of action for Palmitoyl Tetrapeptide-7.

Safety & Risk Analysis

MinimalRare mild irritation

Critical Safety Warning

Black market peptides can be contaminated, mislabeled, or dangerous. Only obtain peptides via a registered doctor and legitimate pharmacy. Never attempt self-administration without professional medical supervision.

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Quick Reference

CategoryCosmetic
Half-LifeN/A (topical)
AdminSubcutaneous
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Medical Note

This compound is for research purposes only. Clinical applications must be directed by a licensed physician.

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