Compendium
Cognitive

P21

P21 is a synthetic peptide derived from CNTF that promotes neurogenesis in the hippocampus. Research in rats shows significant improvements in spatial memory and neuroplasticity.

Protocol

100–300 mcg subcutaneous, daily for 2–4 week cycles

Half-Life

~2 hours

Molecular Structure & Chemistry

6 residues • 77 atoms • Skeletal Formula

Formula

C22H36N6O11S2

Molar Mass

516.6 g/mol

Exact Mass

624.189 Da

Isoelectric Pt

2.81

Charge pH 7

-2.13

GRAVY

+0.23

Hover Cα carbons for residue info

Amino Acid Sequence

GCCLDD

Biological Mechanisms

Hippocampal neurogenesis

Observed in clinical research as a primary mechanism of action for P21.

Memory improvement

Observed in clinical research as a primary mechanism of action for P21.

Neuroprotection

Observed in clinical research as a primary mechanism of action for P21.

Anti-amyloid potential

Observed in clinical research as a primary mechanism of action for P21.

BDNF-independent neurotrophy

Observed in clinical research as a primary mechanism of action for P21.

Safety & Risk Analysis

Limited human dataPotential headacheInjection site reactionsLong-term effects unknown

Critical Safety Warning

Black market peptides can be contaminated, mislabeled, or dangerous. Only obtain peptides via a registered doctor and legitimate pharmacy. Never attempt self-administration without professional medical supervision.

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Quick Reference

CategoryCognitive
Half-Life~2 hours
AdminSubcutaneous
Download Research PDF
Medical Note

This compound is for research purposes only. Clinical applications must be directed by a licensed physician.

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