Compendium

Nootropic Peptides

Neuroprotective and cognition-enhancing peptides that support memory, focus, and brain health.

Cognitive

Cerebrolysin

Cerebrolysin is a peptide mixture from porcine brain tissue containing active neuropeptides. Approved in many countries for Alzheimer's disease and stroke, it has demonstrated neurotrophic and neuroprotective effects.

NeuroregenerationAlzheimer's disease treatment
Cognitive

Cortexin

Cortexin is a polypeptide fraction derived from bovine cerebral cortex. Used clinically in Russia and Eastern Europe for neurological conditions including stroke, cognitive decline, and epilepsy.

NeuroprotectiveCognitive improvement
Cognitive

Dihexa

Dihexa is an angiotensin IV analog that potently promotes synaptogenesis via HGF/MET signaling. It is considered millions of times more potent than BDNF in promoting new neural connections.

SynaptogenesisExtreme cognitive enhancement
Cognitive

Galanin

Galanin is a 29–30 amino-acid neuropeptide widely distributed in the CNS that modulates pain, mood, memory, and feeding behavior through three G-protein coupled receptors (GalR1, 2, 3).

Pain modulationMood regulation
Cognitive

N-Acetyl Selank Amidate

An enhanced, stabilized form of Selank with increased receptor binding affinity. It modulates GABA-A receptors and serotonin/dopamine systems for anxiolysis and cognitive enhancement.

Potent anxiolyticEnhanced cognition
Cognitive

N-Acetyl Semax Amidate

N-Acetyl Semax Amidate has N-acetylation and C-terminal amidation that dramatically increase potency and duration of effect compared to standard Semax.

Enhanced cognitive performanceGreater BDNF upregulation
Cognitive

P21

P21 is a synthetic peptide derived from CNTF that promotes neurogenesis in the hippocampus. Research in rats shows significant improvements in spatial memory and neuroplasticity.

Hippocampal neurogenesisMemory improvement
Cognitive

PACAP-38

Pituitary Adenylate Cyclase-Activating Polypeptide-38 is a neuropeptide with broad neurotrophic, anti-apoptotic, and neuroprotective effects. It stimulates cAMP signaling and modulates stress responses.

NeuroprotectionEnhanced neuroplasticity
Cognitive

Pinealon

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) that penetrates the blood-brain barrier and exerts epigenetic regulatory effects in nervous system and retinal cells.

Cognitive preservationNeuroprotection
Cognitive

Selank

Selank is a synthetic heptapeptide based on tuftsin sequence with added stabilizing amino acids. It modulates the GABAergic system and enhances memory and stress resilience without sedation.

AnxiolyticMemory enhancement
Cognitive

Semax

Semax is a synthetic heptapeptide derived from ACTH(4-10) with added Pro-Gly-Pro for metabolic stability. It upregulates BDNF expression and enhances dopaminergic and serotonergic activity.

Cognitive enhancementNeuroprotection